Method for producing CD4/CD8 double-positive T cells
US11578310B2 · kind B2 · utility
2Cited by
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16Claims
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Key dates
| Filing date | Jun 21, 2017 |
| Grant date | Feb 14, 2023 |
| Priority date | — |
| Expiry date | Apr 14, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for producing CD4/CD8 double-positive T cells, comprising the steps of: (1) culturing pluripotent stem cells in a medium to induce hematopoietic progenitor cells; and (2) culturing the hematopoietic progenitor cells obtained in the step (1) in a medium containing a p38 inhibitor and/or SDF-1 to induce CD4/CD8 double-positive T cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.