Method for the in vitro prognosis of individuals having multiple myeloma and method for the treatment thereof
US11578369B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 31, 2017 |
| Grant date | Feb 14, 2023 |
| Priority date | — |
| Expiry date | Mar 7, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/118
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for in vitro predicting of the outcome of an individual having a multiple myeloma, including the steps of: a) measuring the expression level of at least 5 genes and/or proteins encoded by the 5 genes, the genes being selected in a group including NRP2, REEP1, SV2B, ARRB1, CACNA1G, FBLIM1, FGFR1, IRF6, ITGA9, NOVA2, PPP2R2C, SLC5A1, SORL1, SYT7 and THY1, in a biological sample obtained from the individual; b) calculating a score value from the expression level obtained at step a); c) classifying the individual as having a good prognosis status or a bad prognosis status, by comparing the score value obtained at step b) with a reference score value.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.