Methods for diagnosis and treatment of patients having solid tumors
US11578370B2 · kind B2 · utility
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Key dates
| Filing date | Feb 14, 2018 |
| Grant date | Feb 14, 2023 |
| Priority date | — |
| Expiry date | Apr 23, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for diagnosing a subject as a candidate for removal of a solid tumor without preoperative chemoradiation therapy, and methods for treating patients having solid tumors, who have one or more of genomic instability, elevated double stranded DNA breaks, elevated gamma-H2AX foci, or elevated replication stress and/or double stranded break-signalling (DSB-signalling) biomarkers in peripheral blood lymphocytes (PBLs) are provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.