Humanized antibodies
US11578428B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Apr 1, 2020 |
| Grant date | Feb 14, 2023 |
| Priority date | — |
| Expiry date | Apr 14, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are humanized antibodies in which human germline residues are introduces to the complementarity determining regions (CDRs) of a non-human donor antibody. Also described herein are libraries of antibody variable domains (e.g., phage-display libraries) and methods for screening for humanized antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.