Patent · US Active

Hydrogel systems for skeletal interfacial tissue regeneration applied to epiphyseal growth plate repair

US11583613B2 · kind B2 · utility

0Cited by

4References

14Claims

0Family size

Assignee

University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

Juan M. Taboas · Ann Arbor, US
Jingming Chen · Pittsburgh, US

Key dates

Filing date	Mar 3, 2017
Grant date	Feb 21, 2023
Priority date	—
Expiry date	Mar 28, 2040

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2430/02
WIPO fieldMedical technology
WIPO sectorInstruments

Abstract

Described herein are biomaterials, systems, and methods for guiding regeneration of an epiphyseal growth plate or similar interfacial tissue structures. In one aspect, the disclosed technology can include a biologic material that can comprise one or more of a hydrogel carrier for growth factors and MSCs, chondrogenic and immunomodulatory cytokines, microparticles for prolonged and spatially controlled growth factor delivery; and/or porous scaffold providing mechanical support. The implanted material can be applied via various different modalities depending on the nature of the physeal injury. One modality is an injectable hydrogel and another modality is an implantable hydrogel infused scaffold.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.