Method of making in vivo human small intestine organoids from pluripotent stem cells
US11584916B2 · kind B2 · utility
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Key dates
| Filing date | Oct 16, 2015 |
| Grant date | Feb 21, 2023 |
| Priority date | — |
| Expiry date | Oct 16, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2513/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are methods for making a vascularized hollow organ derived from human intestinal organoid (HIOs). The HIOs may be obtained from human embryonic stem cells (ESC's) and/or induced pluripotent stem cells (iPSCs), such that the HIO forms mature intestinal tissue. Also disclosed are methods for making a human intestinal tissue containing a functional enteric nervous system (ENS).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.