Patent · US Active

Transcriptional control in prokaryotic cells using DNA-binding repressors

US11584918B2 · kind B2 · utility

1Cited by

1References

19Claims

0Family size

Assignee

Eligo Bioscience · FR

Inventors

Jesus Fernandez Rodriguez · Paris, FR
Antonina Krawczyk · Paris, FR
Xavier Duportet · Paris, FR

Key dates

Filing date	Mar 16, 2020
Grant date	Feb 21, 2023
Priority date	—
Expiry date	Jun 21, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2795/00043
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present disclosure relates generally to methods and compositions for transferring a genetic circuit from one prokaryotic cell (“donor cell”) to another prokaryotic cell (“recipient cell” or “target cell” which are used interchangeably herein). More specifically, the present disclosure relates to prokaryotic donor cells comprising (i) a genetic circuit of interest and (ii) one or more expressed transcriptional repressor proteins and the use of said donor cells in the efficient transfer of the genetic circuit into a prokaryotic recipient cell. The genetic circuit includes nucleic acid sequences encoding a RNA molecule or protein of interest.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.