Patent · US Active

Recombinant Escherichia coli and application thereof in screening erythritol-producing strains

US11591374B2 · kind B2 · utility

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Key dates

Filing dateJun 30, 2020
Grant dateFeb 28, 2023
Priority date
Expiry dateSep 16, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/02
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present disclosure discloses recombinant Escherichia coli and application thereof in screening erythritol-producing strains, and belongs to the technical field of microorganisms. The recombinant Escherichia coli used in a method for screening an erythritol-producing strain disclosed by the present disclosure can well perform positive correlation induction on erythritol with different concentrations, so that the method for screening the erythritol-producing strain has the advantage of high sensitivity. High-concentration glucose is usually adopted as a fermentation substrate when erythritol is produced in a fermentation mode in the industry, but the method for screening the erythritol-producing strain disclosed by the present disclosure can overcome the interference of the high-concentration glucose, and under the interference of the high-concentration glucose, the recombinant Escherichia coli used in the method for screening the erythritol-producing strain can still well perform positive correlation induction on erythritol with different concentrations, and the correlation is higher than that without the interference of the glucose. Therefore, the method for screening the eryth…

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