Patent · US Active

Biological binding molecule

US11591391B2 · kind B2 · utility

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0References

10Claims

0Family size

Assignee

AVA LIFESCIENCE GMBH · DE

Inventors

Ulrich Birsner · Freiburg im Breisgau, DE
Hassan Jumaa · Blaubeuren, DE
Holger Klapproth · Glückstadt, DE
Marc A. KESSEMEIER · Emmendingen, DE

Key dates

Filing date	Jul 5, 2018
Grant date	Feb 28, 2023
Priority date	—
Expiry date	Sep 23, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/705
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the field of the production, identification and selection of biological binding molecules such as antibodies or fragments thereof, as well as to their use in the therapy and prophylaxis of cancer diseases, such as, in particular, malignant B-cell neoplasia.The binding molecules are able to selectively bind to autonomously active or autonomously activated B-cell receptors, the autonomously active or autonomously activated B-cell receptors being characterized by the presence of structural domains to which the binding molecule selectively binds and which are responsible for the autonomously active or autonomously activated state of the B-cell receptors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.