Cytotoxic and anti-mitotic compounds, and methods of using the same
US11591405B2 · kind B2 · utility
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36References
18Claims
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Key dates
| Filing date | Jul 26, 2019 |
| Grant date | Feb 28, 2023 |
| Priority date | — |
| Expiry date | Jul 26, 2039 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH10K59/1201
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. Also disclosed are compositions having the structure: (T)-(L)-(D), wherein (T) is a targeting moiety, (L) is an optional linker, and (D) is a compound having cytotoxic and/or anti-mitotic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.