Method for the diagnosis, prognosis and treatment of cancer metastasis
US11591599B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 3, 2018 |
| Grant date | Feb 28, 2023 |
| Priority date | — |
| Expiry date | Dec 31, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This study describes a method to determine the likelihood of the development of metastasis in a subject suffering from cancer, in addition to a method to design a customized therapy in a subject suffering from cancer, in particular breast, colon, lung, kidney and thyroid cancer, based on the determination of the expression level of one or more genes whose expression is modulated by an increase in c-MAF expression. It also describes a method for the identification of marker genes with a propensity for metastatic cancer based on inducing the modulation of the c-MAF expression Finally, the use of PTHLH and PODXL inhibitors and RERG activators in the treatment and/or prevention of the cancer, in particular breast, colon, lung, kidney and thyroid cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.