Methods and systems for the rapid detection of bacteria using recombinant bacteriophage to express an indicator subunit
US11591633B2 · kind B2 · utility
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Key dates
| Filing date | Sep 11, 2020 |
| Grant date | Feb 28, 2023 |
| Priority date | — |
| Expiry date | Dec 15, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/90241
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methods and systems for rapid detection of microorganisms such as bacteria in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene encoding one subunit of an indicator protein. The specificity of the bacteriophage allows detection of a particular bacteria of interest and an indicator signal may be amplified to optimize assay sensitivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.