Systems and methods for ocular drug delivery

US11596545B2 · kind B2 · utility

Assignee

• CLEARSIDE BIOMEDICAL, INC. · US

Inventors

• Rafael Victor Andino · Grayson, US
• Thomas E. Godfrey · Moore, US
• Shelley Eckert HANCOCK · Atlanta, US
• Samirkumar Patel · Atlanta, US
• Keleigh Jo Mahn · Atlanta, US
• Jesse Yoo · Snellville, US
• Vladimir ZARNITSYN · Atlanta, US

Key dates

• Filing date: Nov 1, 2018
• Grant date: Mar 7, 2023
• Expiry date: Sep 1, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Devices, methods, and kits for ocular drug delivery are described herein. An apparatus can include a housing, an energy storage member, a barrel, and a hub. The housing contains the energy storage member. A proximal end portion of the barrel is coupled to a distal end portion of the housing. The barrel is configured to contain medicament and includes at least a portion of a piston and an elastomeric member. The piston is configured to move the elastomeric member within the barrel in response to a force produced by the energy storage member. The hub is coupled to a distal end portion of the barrel. An inner surface of the hub defines a nozzle through which the medicament flows when the elastomeric member moves within the barrel. The nozzle and the energy storage member are collectively configured to produce a fluid jet to access a target location within an eye.