Patent · US Active

RNA encoding an antibody

US11596699B2 · kind B2 · utility

8Cited by
0References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 28, 2017
Grant dateMar 7, 2023
Priority date
Expiry dateOct 8, 2039

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a RNA encoding an antibody or a fragment or variant thereof and a composition, in particular a passive vaccine, comprising such an RNA. The present invention further relates to the use of such an RNA or of such a composition for treatment of tumours and cancer diseases, cardiovascular diseases, infectious diseases, autoimmune diseases, virus diseases and monogenetic diseases, e.g. also in gene therapy. The present invention also relates to a combination of at least two modified RNA's, in particular wherein one RNA encodes a heavy chain variable region of an antibody and another RNA encodes the corresponding light chain variable region of said antibody.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.