URAT1 inhibitor for promoting uric acid excretion
US11597725B2 · kind B2 · utility
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10Claims
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Assignee
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Key dates
| Filing date | May 25, 2018 |
| Grant date | Mar 7, 2023 |
| Priority date | — |
| Expiry date | Jul 5, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/052
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention belongs to the field of medicinal chemistry. Specifically disclosed is a class of URAT1 inhibitors for promoting uric acid excretion, which are compounds as represented by the structure of formula (I) or pharmaceutically acceptable salts thereof. Experiments show that the compounds provided by the present invention have a very good inhibitory effect on the transport of uric acid by hURAT1 in HEK293 transfected cells, and that such compounds have a good application prospect in the treatment of hyperuricemia or gout.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.