Tropomyosin receptor kinase inhibitor, preparation method therefor and use thereof
US11597729B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Jun 6, 2019 |
| Grant date | Mar 7, 2023 |
| Priority date | — |
| Expiry date | Oct 16, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed in the present invention are a pyrazolo [1,5-a]pyrimidine derivative having a structure of formula (I), a pharmaceutical composition comprising the compound of formula (I), and use of the compound in the preparation of a medicament for preventing or treating diseases associated with tropomyosin receptor kinases, in particular for preventing or treating cancers associated with tropomyosin receptor kinases. Each substituent in formula (I) has the same definition as that in the description.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.