Chiral phosphoramidite auxiliaries and methods of their use
US11597744B2 · kind B2 · utility
2Cited by
121References
20Claims
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Key dates
| Filing date | Jul 2, 2018 |
| Grant date | Mar 7, 2023 |
| Priority date | — |
| Expiry date | Nov 4, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are chiral phosphoramidite auxiliary compositions for diastereoselective synthesis of stereochemically enriched oligonucleotides, and nucleoside phosphoramidite compounds comprising the same. Exemplary structures of the chiral phosphoramidite auxiliary compositions include Formulas (IA) and (IB).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.