Means and methods for treating herpesvirus infection
US11602560B2 · kind B2 · utility
1Cited by
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20Claims
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Key dates
| Filing date | Feb 28, 2017 |
| Grant date | Mar 14, 2023 |
| Priority date | — |
| Expiry date | Mar 16, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/16652
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides herpesviruses, such as EBV, which lack at least one viral miRNA. Such herpesviruses lacking at least one viral miRNA are advantageously not capable of packaging their genome into the capsid, thereby producing HVLPs, which are substantially free of their herpesvirus genome or the nucleic acid molecule encoding the proteinaceous part of the HVLP and viral miRNA. Such HVLPs may be used as vaccine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.