Methods for reducing contamination in a biological substance

US11602585B2 · kind B2 · utility

Assignee

• CytoSorbents, Inc. · US

Inventors

• Phillip P. Chan · Cherry Hill, US
• Vincent J. Capponi · Monmouth Junction, US
• Thomas D. Golobish · Princeton, US
• Humayra Begum Ali · Princeton, US

Key dates

• Filing date: Apr 26, 2017
• Grant date: Mar 14, 2023
• Expiry date: Apr 1, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08J2353/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are materials and methods of reducing contamination in a biological substance or treating contamination in a subject by one or more toxins comprising contacting the biological substance with an effective amount of a sorbent capable of sorbing the toxin, wherein the sorbent comprises a plurality of pores ranging from 50 Å to 40,000 Å with a pore volume of 0.5 cc/g to 5.0 cc/g and a size of 0.05 mm to 2 cm and sorbing the toxin. Also provided are kits to reduce contamination by one or more toxins in a biological substance comprising a sorbent capable of sorbing a toxin, wherein the sorbent comprises a plurality of pores ranging from 50 Å to 40,000 Å with a pore volume of 0.5 cc/g to 5.0 cc/g and a size of 0.05 mm to 2 cm and a vessel to store said sorbent when not in use together with packaging for same.