Divalent nucleobase compounds and uses therefor
US11603369B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Sep 26, 2017 |
| Grant date | Mar 14, 2023 |
| Priority date | — |
| Expiry date | Apr 30, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5308
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described herein are divalent nucleobases that each binds two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone, such as in a γ-peptide nucleic acid (γPNA). Also provided are genetic recognition reagents comprising one or more of the divalent nucleobases and a nucleic acid or nucleic acid analog backbone, such as a γPNA backbone. Uses for the divalent nucleobases and monomers and genetic recognition reagents containing the divalent nucleobases also are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.