Patent · US Active

Peptide nucleic acid conjugates

US11603388B2 · kind B2 · utility

1Cited by

16References

20Claims

0Family size

Assignee

Ventana Medical Systems, Inc. · US

Inventors

Rui Hong · Oro Valley, US
Aoune Barhoumi · Oro Valley, US

Key dates

Filing date	Jun 1, 2020
Grant date	Mar 14, 2023
Priority date	—
Expiry date	Jan 15, 2041

Classification

Technology area (CPC G)Physics
CPC primaryG01N2458/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure is directed to conjugates of a specific binding entity and an oligomer, i.e. [Specific Binding Entity]-[Oligomer]n, wherein n is an integer ranging from 1 to 12, and where the Oligomer includes, in some embodiments, a PNA sequence having at least one substituent at a gamma carbon position. In some embodiments, the substituent at the gamma carbon position, e.g. an amino acid, a peptide, a miniPEG, or a polymer, includes at least one reporter moiety.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.