Inhibitors of RAC1 and uses thereof for inducing bronchodilatation
US11607419B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 6, 2018 |
| Grant date | Mar 21, 2023 |
| Priority date | — |
| Expiry date | Jun 14, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/62
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns a compound having the following formula (I): wherein: —A is in particular —N(R′a)—C(═O)—R, R′a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): —X is in particular chosen from the group consisting of: —SO2—N(R′b)—, R′b being H or a (C1-C6)alkyl group, —N(R″b)—SO2—, R″b being H or a (C1-C6)alkyl group, —CO—NH—, and —NH—CO—, for use for the treatment of pathologies characterized by bronchoconstriction, such as asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.