Uses of labeled HSP90 inhibitors

US11607465B2 · kind B2 · utility

Assignee

• Sloan Kettering Institute for Cancer Research · US

Inventors

• Gabriela Chiosis · New York, US
• Naga Vara Kishore Pillarsetty · New York, US
• Jason S. Lewis · New York, US
• Steven M. Larson · New York, US
• Tony Taldone · Elmont, US
• Mary L. Alpaugh · Los Angeles, US
• Erica M. Gomes-DaGama · New Rochelle, US

Key dates

• Filing date: Jul 21, 2020
• Grant date: Mar 21, 2023
• Expiry date: Jul 21, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

This invention concerns various methods of using labeled HSP90 inhibitors to improve treatment of cancer patients with HSP90 inhibitors, including ex vivo and in vivo methods for determining whether a tumor will likely respond to therapy with an HSP90 inhibitor.