Tumor and immune cell imaging based on PD-L1 expression

US11607466B2 · kind B2 · utility

Assignee

• THE JOHNS HOPKINS UNIVERSITY · US

Inventors

• Sridhar Nimmagadda · Baltimore, US
• Martin G. Pomper · Baltimore, US
• Samit Chatterjee · Baltimore, US
• Wojciech Lesniak · Owings Mills, US
• Dhiraj Kumar · Calabasas, US

Key dates

• Filing date: Dec 21, 2017
• Grant date: Mar 21, 2023
• Expiry date: Jun 24, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The presently disclosed subject matter provides compositions, kits, and methods comprising imaging agents that can detect Programmed Death Ligand 1 (PD-L1). The presently disclosed imaging agents can be used to detect diseases and disorders, such as cancer, infection, and inflammation, in a subject.