Patent · US Active

Compounds and methods for treating tight junction permeabtility

US11608359B2 · kind B2 · utility

0Cited by
27References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 25, 2019
Grant dateMar 21, 2023
Priority date
Expiry dateFeb 25, 2039

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides Larazotide derivative compositions that resist protease degradation, and in various embodiments, do not demonstrate an inverse dose response, and/or can be delivered at higher doses without loss of potency or efficacy, thereby allowing improved therapy and more desirable dosing schedules.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.