Humanized anti-TPBG antibody, preparation method therefor, conjugate thereof, and applications
US11608384B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Apr 4, 2018 |
| Grant date | Mar 21, 2023 |
| Priority date | — |
| Expiry date | Apr 24, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a humanized anti-TPBG antibody, a preparation method therefor, a conjugate thereof, and applications. The humanized anti-TPBG antibody comprises: (a), a framework region comprising a residue of a human antibody framework region; and (b) one or more CDRs of a light-chain variable region as shown in the SEQ ID NO:4 or 8 or one or more CDRs of a heavy-chain variable region as shown in the SEQ ID NO:2 or 6.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.