Cell growth with mechanical stimuli
US11608486B2 · kind B2 · utility
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602References
20Claims
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Key dates
| Filing date | Dec 22, 2017 |
| Grant date | Mar 21, 2023 |
| Priority date | — |
| Expiry date | Jan 10, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M27/14
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Embodiments for loading and expanding particular cell types are described. Embodiments may include the use of hollow fiber membranes with particular characteristic such as hollow fibers with inner diameters that provide mechanical stimulus (e.g., radius of curvature greater than a dimension of a cell). In addition, embodiments may provide for manipulation of flow rates and other features that also provide mechanical stimuli and promote or enhance the growth of particular types of cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.