Patent · US Active

Detection of autoantibodies for diagnosing degenerative diseases of the skeletal system

US11609231B2 · kind B2 · utility

0Cited by

1References

14Claims

0Family size

Assignee

UNIVERSITÄT ZU KÖLN · DE

Inventors

Andreas Klatt
Johannes Ruthard · Hürth, DE
Benedikt Ostendorf · Neuss, DE
Matthias Schneider · Dossenheim, DE
Georg Pongratz · Adlersberg, DE
Gabriele Hermes · Cologne, DE

Key dates

Filing date	Dec 12, 2018
Grant date	Mar 21, 2023
Priority date	—
Expiry date	Oct 12, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/56
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Methods, kits, and active ingredients for diagnosing or treating arthritis or a degenerative disease of the skeletal system, or for selection of subjects for therapy. The methods for diagnosing arthritis involve the detection of an autoantibody, which is associated with arthritis, or excluding the presence of an autoantibody against collagen II. The methods for diagnosing a degenerative disease of the skeletal system, involve the detection of an autoantibody against thrombospondin-4 or COMP. The kits contain a detection agent for an autoantibody and can be used for diagnosing arthritis or a degenerative disease of the skeletal system. The active ingredient can be used for treating or preventing autoimmune-associated arthritis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.