Transdermal therapeutic system for administering water-soluble peptides and polypeptides

US11612571B2 · kind B2 · utility

Assignee

• LTS Lohmann Therapie-Systeme AG · DE

Inventors

• Bodo Asmussen · Bendorf, DE
• Michael Horstmann · Neuwied, DE
• Christoph Schmitz · Euskirchen, DE
• Mohammad Sameti · Bonn, DE
• Yves-Thorsten Przybylla · Nickenich, DE
• Rolf Pracht · Höhr-Grenzhausen, DE

Key dates

• Filing date: Jan 19, 2008
• Grant date: Mar 28, 2023
• Expiry date: Oct 1, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a transdermal therapeutic system for the controlled release of water-soluble pharmaceutical active ingredients from an aqueous phase, comprising an occlusive back layer, a central device facing the skin for releasing the agent, an adhesive layer concentrically surrounding the dispensing device and a removable protective film. Said device is made from a stationary solid phase and a liquid phase containing the active ingredient in aqueous solution, the solid phase being formed from a solid with a fleecy or spongy structure.