Substituted imidazo[1,5-a]pyrazines for modulation of IRE1

US11613544B2 · kind B2 · utility

Assignees

• The Regents of the University of California · US
• University of Washington through its Center for Commercialization · US

Inventors

• Bradley Backes · San Francisco, US
• Dustin J. Maly · Seattle, US
• Scott A. Oakes · San Francisco, US
• Feroz R. Papa · Oakland, US
• Gayani Perera · Nugegoda, LK
• Likun Wang · 安丰镇, CN

Key dates

• Filing date: Sep 24, 2020
• Grant date: Mar 28, 2023
• Expiry date: Sep 24, 2040

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein, inter alia, are certain substituted imidazo[1,5-a]pyrazines of formula (I) and methods of using the same for modulating the activity of Ire1.