Method for purifying mesenchymal stem cells to improve transplantation efficiency
US11613733B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | May 11, 2018 |
| Grant date | Mar 28, 2023 |
| Priority date | — |
| Expiry date | Jan 7, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/1353
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for purifying and enriching mesenchymal stem cells (MSCs) simply and efficiently. Separation of cells expressing CD73 protein on the surface from fresh tissue isolated from a living body allows purification and enrichment of MSCs easily and efficiently. MSCs may be selectively isolated with a single antibody before culturing to establish a culture system of mesenchymal stem cells that enhances the engraftment efficiency in the transplanted site.
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