T cell receptors that bind to NY-ESO-1 and methods of use thereof

US11613764B2 · kind B2 · utility

Assignee

• MiNK Therapeutics, Inc. · US

Inventors

• Marc van Dijk · Bosch en Duin, NL
• Volker Seibert · Lörrach, DE
• Cornelia Anne Mundt · Lörrach, DE
• Arthur Andrew Hurwitz · Bedford, US
• Mark A. Exley · Sharon, US
• Benjamin Jacob Wolf · Seattle, US
• Daniel Leventhal · Medford, US
• Sébastien Lalevée · Village-Neuf, FR
• Reed Masakayan · Lincoln, US

Key dates

• Filing date: Jul 15, 2019
• Grant date: Mar 28, 2023
• Expiry date: Oct 5, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are TCRs (e.g., TCRs that bind to NY-ESO-1), cells and pharmaceutical compositions comprising these TCRs, nucleic acids encoding these TCRs, expression vectors and host cells for making these TCRs, and methods of treating a subject using these TCRs.