Methods and compositions for delivery of biotin to mitochondria
US11617739B2 · kind B2 · utility
2Cited by
1References
31Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 16, 2022 |
| Grant date | Apr 4, 2023 |
| Priority date | — |
| Expiry date | Sep 16, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2500/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Certain exemplary embodiments are directed to a biologically active composition of matter (and uses thereof) configured for targeted delivery of biotin to mitochondria, the composition comprising a first D-biotin conjugated to a water-soluble, cell-permeable, peptide sequence, wherein the peptide sequence is selected from a polypeptide group with an alternating aromatic-cationic motif.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.