VAP polypeptide and use thereof in preparation of drug for targeted diagnosis and treatment of tumor
US11622990B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Dec 6, 2017 |
| Grant date | Apr 11, 2023 |
| Priority date | — |
| Expiry date | May 21, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/107
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided in the present invention are highly stable D-configuration polypeptides DVAP and SVAP having a high binding activity to the GRP78 protein, and also provided are an L-configuration polypeptide LVAP and a DVAP-or SVAP-modified model drug and a macromolecule carrier material, and the use thereof in the construction of a tumour image and a drug-delivery system for targeted treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.