PDX1 pancreatic endoderm cells in cell delivery devices and methods thereof
US11623023B2 · kind B2 · utility
1Cited by
76References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 10, 2016 |
| Grant date | Apr 11, 2023 |
| Priority date | — |
| Expiry date | Nov 3, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2535/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are devices and methods for transplanting cells, such as pancreatic endoderm cells, into a host. The devices include a non-woven fabric external to a cell-excluding membrane, and the non-woven fabric and/or cell-excluding membrane can be perforated. Treatment of the host with immunosuppressive reagents, required to inhibit allograft rejection due to perforations in the cell delivery device, does not compromise maturation or function of transplanted pancreatic endoderm cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.