Uracil compound as c-MET/AXL inhibitor

US11623923B2 · kind B2 · utility

Assignee

• Medshine Discovery Inc. · CN

Inventors

• Jinping LI · Shanghai, CN
• Xiongbin XU · Shanghai, CN
• Gang Li · Beijing, CN
• Lihong Hu · Shanghai, CN
• Charles Z. Ding · San Mateo, US
• Yaling Zhou · Shanghai, CN
• Guoping HU · Shanghai, CN
• Jian Li · Shanghai, CN
• Shuhui CHEN · Shanghai, CN

Key dates

• Filing date: Nov 23, 2018
• Grant date: Apr 11, 2023
• Expiry date: Jan 25, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided are a uracil compound represented by Formula (IV) or a pharmaceutically acceptable salt thereof and a pharmaceutical composition of the same. Also provided is a use thereof as a c-MET/AXL inhibitor in preparing a c-MET/AXL-inhibiting drug or a drug for treating a tumor.