Enrichment of mutated cell free nucleic acids for cancer detection
US11624064B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Jun 13, 2017 |
| Grant date | Apr 11, 2023 |
| Priority date | — |
| Expiry date | Apr 23, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/80
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are methods of enriching mutated cell free nucleic acids for detection and diagnosis of cancer. Also provided are methods using a CRISPR-Cas system to target and deplete unwanted more abundant cell free nucleic acid sequences thereby enriching for less abundant sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.