System for quantitative differential phase contrast microscopy with isotropic transfer function
US11624900B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 24, 2019 |
| Grant date | Apr 11, 2023 |
| Priority date | — |
| Expiry date | Feb 7, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B21/34
- WIPO fieldOptics
- WIPO sectorInstruments
Abstract
A system for quantitative differential phase contrast microscopy with isotropic transfer function utilizes a modulation mechanism to create a detection light field having a radial or other axial orientation of optical intensity gradient or other distribution. A condenser generates an off-axis light field to project onto an object under examination, thereby generating an object light field, which is then guided to an image capturing device through an objective lens for capturing images. A differential phase contrast algorithm is applied to the images for obtaining a phase, thereby a depth information corresponding to the phase can be obtained to reconstruct the surface profile of the object.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.