Mineral coated microparticles for gene delivery in chronic wound therapy
US11628227B2 · kind B2 · utility
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Key dates
| Filing date | Jul 5, 2018 |
| Grant date | Apr 18, 2023 |
| Priority date | — |
| Expiry date | Jul 5, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are formulations for providing a therapeutic bioactive polypeptide to injured tissue. Formulations include mineral coated microparticles wherein a polynucleotide is adsorbed to the mineral layer. Other formulations include a carrier including mineral coated microparticles wherein mineral coated microparticles include a polynucleotide. Also disclosed are methods for sustained delivery of a bioactive polypeptide and methods for treating chronic wounds using a formulation for providing sustained delivery of the bioactive peptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.