Patent · US Active

Single-sheath microfluidic chip

US11628439B2 · kind B2 · utility

0Cited by
166References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 13, 2020
Grant dateApr 18, 2023
Priority date
Expiry dateJan 13, 2040

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01L2300/0858
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Microfluidic devices and methods for focusing components in a fluid sample are described herein. The microfluidic devices feature a microfluidic chip having a micro-channel having a constricting portion that narrows in width, and a flow focusing region downstream of the micro-channel. The flow focusing region includes a positively sloping bottom surface that reduces a height of the flow focusing region and sidewalls that taper to reduce a width of the flow focusing region, thereby geometrically constricting the flow focusing region. The devices and methods can be utilized in sex-sorting of sperm cells to improve performance and increase eligibility.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.