Dual cytokine fusion proteins comprising IL-10
US11629178B2 · kind B2 · utility
13Cited by
8References
6Claims
0Family size
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Key dates
| Filing date | Mar 1, 2022 |
| Grant date | Apr 18, 2023 |
| Priority date | — |
| Expiry date | Mar 1, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The application relates to a dual cytokine fusion protein composition, pharmaceutical composition, and/or formulation thereof comprising IL-10 or IL-10 variant molecules fused to a single chain variable fragment scaffolding system and a second cytokine, where the second cytokine is linked in the hinge region of the scFv. The application also relates to methods of using the dual cytokine fusion protein composition for treating cancer, inflammatory diseases or disorders, and immune and immune mediated diseases or disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.