Sample dispatching with fluidic sample retaining

US11630090B2 · kind B2 · utility

Assignee

• AGILENT TECHNOLOGIES, INC. · US

Inventors

• Thomas Ortmann · Ittersbach, DE
• Thomas Glauner · Raumünzach, DE

Key dates

• Filing date: Jul 30, 2020
• Grant date: Apr 18, 2023
• Expiry date: Feb 26, 2041

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/385
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A sample dispatcher for a fluid separation apparatus includes a sampling path including a sampling volume, a sampling unit, and a retaining unit. The sampling unit receives a fluidic sample, and the sampling volume temporarily stores an amount of the received sample. The retaining unit receives and retains from the sampling volume at least a portion of the stored sample, and has different retention characteristics for different components of the sample. A switching unit is coupled to the sampling path, a sampling fluid drive, a mobile phase drive, and a separating device. In a feed injection configuration of the switching unit, the mobile phase drive, the separating device, and the sampling path are coupled together in a coupling point for combining a flow from the sampling fluid drive containing the fluidic sample retained by the retaining unit with a flow of the mobile phase from the mobile phase drive.