Method for diagnosing anomalies in the coagulation of blood
US11630101B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 15, 2016 |
| Grant date | Apr 18, 2023 |
| Priority date | — |
| Expiry date | Jan 11, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a method for diagnosing anomalies in the coagulation of blood, comprising the following successive steps: a) placing a sample of total blood in a holder containing two pairs of electrodes connected to an apparatus generating an electrical current; b) incubating this sample for 60 to 180 seconds in the presence of calcium; c) adding to this sample tissue factor in a concentration high enough to trigger the coagulation of the blood; d) measuring the impedance variation between the electrodes as a function of time, for a period comprised between 10 and 30 minutes from step (c), and generating a curve of the impedance values as a function of time; e) comparing the value of the area under the curve generated in step (d) with the value of an area under a reference curve.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.