Dental varnishes that release specifically targeted antimicrobial peptides and/or fluoride
US11633341B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 12, 2018 |
| Grant date | Apr 25, 2023 |
| Priority date | — |
| Expiry date | Sep 30, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/882
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In various embodiments a dental varnish system having improved peptide release and fluoride release properties is provided. In various embodiments a dental varnish system that provides release of an antimicrobial peptide, or specifically targeted antimicrobial peptide (STAMP), e.g., the peptide C16G2, is provided, with or without a fluoride. In various embodiments, a dental varnish system that provides release of a fluoride, with or without an antimicrobial peptide or STAMP is provided. In certain embodiments the dental varnish system comprises a first component that is a dry powder, said first component comprising a an antimicrobial peptide, with or without a fluoride, and a bulking agent, and a second component that is a fluid, said second component comprising a varnish solution, where combination of said first component with said second component provides a varnish formulation for application to the surface of a tooth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.