Soft chew pharmaceutical formulations

US11633361B2 · kind B2 · utility

Assignee

• First Time US Generics LLC · US

Inventors

• Manesh Dixit · Sunrise, US
• Vaibhav L. PAWAR · Broomall, US
• Rushi R. Patel · Broomall, US
• Mineshkumar D. Patel · Broomall, US
• Amol SOMWANSHI · Navi Mumbai, IN

Key dates

• Filing date: Jun 5, 2020
• Grant date: Apr 25, 2023
• Expiry date: Jun 5, 2040

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/546
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A product and process of manufacturing an edible soft-chewable dosage form for the delivery of pharmaceutically active ingredients or nutritional agents orally to an animal or human subject, by forming a granulated soft-chew mass by appropriate mixing and sifting steps, and forming tablets with a compression press. Such soft-chew dosage forms have hardness of less than about two kilopond (2 kp) and friability of less than about one percent (1%) at three-hundred (300) rotations when measured according to the United States Pharmacopeia (USP) test. The process for manufacturing such compressed soft-chew tablets employs compression (tablet) pressing equipment to produce soft-chew tablets of consistent weight and texture.