Devices and methods for sample analysis

US11633738B2 · kind B2 · utility

Assignee

• Abbott Laboratories · US

Inventors

• Jeffrey B. Huff · Carlsbad, US
• Mark A. Hayden · Ingleside, US
• Peter J. Karabatsos · Glencoe, US
• Andrew Fischer · Euless, US
• John Robinson · Spanish Fork, US
• Shelley R. Holets-McCormack · Waukegan, US
• Sophie Laurenson · Basel, CH

Key dates

• Filing date: Oct 3, 2017
• Grant date: Apr 25, 2023
• Expiry date: Oct 3, 2037

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/0427
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.