Patent · US Active

Non-neuronal snare-cleaving botulinum neurotoxins

US11634460B2 · kind B2 · utility

0Cited by

0References

18Claims

0Family size

Assignee

IPSEN BIOPHARM LIMITED · GB

Inventors

Thomas Binz · Hannover, DE
Stefan SIKORRA · Wrexham, GB

Key dates

Filing date	Jan 29, 2019
Grant date	Apr 25, 2023
Priority date	—
Expiry date	Jan 29, 2039

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a modified botulinum neurotoxin A (BoNT/A) L-chain protease that demonstrates enhanced cleaveage of human SNAP-23 (hSNAP-23) relative to unmodified (wild-type) BoNT/A L-chain protease, together with the use thereof for cleaving hSNAP-23.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.