Patent · US Active

Diagnostic method

US11634487B2 · kind B2 · utility

0Cited by

1References

8Claims

0Family size

Inventors

Ulrich Birsner · Freiburg im Breisgau, DE
Hassan Jumaa · Blaubeuren, DE
Holger Klapproth · Glückstadt, DE
Marc A. KESSEMEIER · Emmendingen, DE

Key dates

Filing date	Jul 5, 2018
Grant date	Apr 25, 2023
Priority date	—
Expiry date	Apr 2, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/705
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the field of production, identification and selection of biological binding molecules such as antibodies or fragments thereof, as well as to diagnostic procedures using them in the diagnosis of cancers, in particular malignant B-cell neoplasia. The binding molecules are able to selectively bind to autonomously active or autonomously activated B-cell receptors, the autonomously active or autonomously activated B-cell receptors being characterized by the presence of structural domains to which the binding molecule selectively binds and which are responsible for the autonomously active or autonomously activated state of the B-cell receptors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.