Anti-TREM2 antibodies and methods of use thereof

US11634489B2 · kind B2 · utility

Assignee

• Alector LLC

Inventors

• Tina SCHWABE · San Francisco, US
• Eric J. Brown · San Francisco, US
• Philip Kong · San Francisco, US
• Ilaria TASSI · San Francisco, US
• Seung-Joo Lee · Goyang-si, KR
• Arnon Rosenthal · Woodside, US
• Robert Pejchal · Hartford, US
• Nels P. Nielson · Cambridge, US

Key dates

• Filing date: Mar 30, 2020
• Grant date: Apr 25, 2023
• Expiry date: Mar 30, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 or human TREM2, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.