Patent · US Active

Dimers and use thereof

US11634492B2 · kind B2 · utility

1Cited by

2References

14Claims

0Family size

Assignee

JIANGSU ALPHAMAB BIOPHARMACEUTICALS CO., LTD. · CN

Inventors

Ting Xu · Berkeley, US
Kangping Guo · Suzhou, CN
Dong Yang · Suzhou, CN
Pilin Wang · Suzhou, CN
Yuhao Jin · Suzhou, CN
Xiaoxiao Wang · Tangxia, CN

Key dates

Filing date	Apr 13, 2021
Grant date	Apr 25, 2023
Priority date	—
Expiry date	Apr 13, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure provides a dimer formed by two polypeptide chains, with each of the two polypeptide chains comprising an antibody Fc subunit, wherein the dimer comprises two or more immunoglobulin single variable domains (ISVDs), at least one of the ISVDs is specific for PD-L1, and at least one of the ISVDs is specific for CTLA4.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.